Neuropathology of Multiple Sclerosis and the Specificity of Motor Rehab
Multiple Sclerosis (MS) is a chronic, autoimmune inflammatory neurodegenerative disorder in which autoreactive T-cells breach the blood-brain barrier to attack the myelin sheath insulating axons in the brain, spinal cord, and optic nerves. Demyelination and axonal transection produce focal sclerotic plaques, severely impeding saltatory conduction.
Unlike static neurological conditions, MS is dynamic and unpredictable, whether presenting as Relapsing-Remitting (RRMS) or Progressive (SPMS/PPMS) phenotypes. Patients confront a complex symptom triad: central lassitude fatigue unrelated to physical exertion, spastic paraparesis, and cerebellar ataxia with intention tremor.
This biological volatility demands clinical sophistication. Overly aggressive exercise can trigger transient neurological worsening (conduction failure), while prolonged sedentariness causes disuse atrophy and joint contractures. Bidaya designs calibrated home programs that build strength and balance while strictly respecting physiological energy reserves.
